Dimethyl Sulfoxide (DMSO) is garnering attention in natural health circles for its anti-inflammatory and analgesic properties. While it’s FDA-approved only for interstitial cystitis, anecdotal reports and preliminary studies suggest potential benefits for various conditions, including tinnitus.

What Is DMSO?

DMSO is a colorless, odorless liquid derived from lignin, a byproduct of wood processing. It’s known for its ability to penetrate biological membranes, making it a unique carrier for other substances. Its anti-inflammatory and antioxidant properties have led to its use in alternative medicine, though scientific consensus on its efficacy for various conditions remains limited.

DMSO and Tinnitus: What the Research Says

Tinnitus, characterized by ringing or buzzing in the ears, affects millions worldwide. A 1975 study explored the use of DMSO in treating subjective tinnitus of unknown origin. In this study, 15 patients received topical DMSO applications in the external auditory canal, combined with intramuscular injections containing DMSO and vasodilatory agents. Results showed complete symptom resolution in nine patients, with improvements in others. However, the study’s small sample size and lack of control group limit the generalizability of these findings. Reddit+6Scribd+6ResearchGate+6PubMed+1ResearchGate+1

Potential Mechanisms of Action

The proposed mechanisms by which DMSO may alleviate tinnitus include:

These mechanisms are theoretical and require further research for validation.

Safety and Precautions

While DMSO is generally considered safe when used appropriately, several precautions are necessary:

  • Skin Absorption: DMSO can carry other substances through the skin, potentially introducing harmful chemicals into the body.

  • Concentration Matters: High concentrations may cause skin irritation or other adverse effects.

  • Medical Supervision: Consult a healthcare professional before using DMSO, especially if you have underlying health conditions or are taking other medications.WikipediaScribd+1PubMed Central+1

Alternative Treatments for Tinnitus

While DMSO’s role in tinnitus treatment remains uncertain, other evidence-based approaches include:

  • Cognitive Behavioral Therapy (CBT): Helps manage the emotional response to tinnitus.

  • Sound Therapy: Uses external noise to mask tinnitus sounds.

  • Tinnitus Retraining Therapy (TRT): Combines counseling and sound therapy to habituate patients to tinnitus.

  • Medications: In some cases, antidepressants or anti-anxiety medications may be prescribed.

Conclusion

DMSO presents an intriguing, yet unproven, option for tinnitus management. While early studies and anecdotal reports offer some hope, comprehensive clinical trials are necessary to establish its efficacy and safety. Patients should approach DMSO with caution and consult healthcare professionals before considering its use.